Our New Mexico casino is open 24/7 daily. Saturdays in. Learn More. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. . Unwind. Colorful bingo cards and round bingo balls w/numbers. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. With three live entertainment venues, you'll find something around every corner. It's a warm, friendly environment with slot machines. #1 Best Value of 24 Mexico Casino Hotels ; 2. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. Indulge. Swirls of Cash. No Smoking Facility. The Travel center includes a casino area with 45 slot machines. A warm and friendly environment with slot machines at the Main Casino. Win. These casinos and gaming sites are owned by 14 New Mexico. at Isleta Resort & Casino. Sky City Casino is open 24 hours daily. #2 Best Value of 24 Mexico. Must be 21+. Upcoming Events. Seadust Cancun Family Resort · 6, reviews. 1. Excite. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. The Pyramid Cancun · 4, reviews. Open 24 hours, 7 days a week! What's happening.